Benefits
How Astaxanthin Works Against Inflammation
Natural astaxanthin helps regulate key inflammatory pathways, including NF-κB, helping reduce the production of pro-inflammatory mediators. It has been extensively studied for its role in managing oxidative stress and inflammation.
Inhibiting NF-κB activation
NF-κB is one of the main signals that triggers an inflammatory response. Astaxanthin helps reduce its activation, lowering the expression of inflammation-related genes.
Suppressing pro-inflammatory cytokines
Astaxanthin helps reduce TNF-α, IL-1β and IL-6 , the molecules that maintain and amplify inflammation.
Inhibiting inflammatory enzymes
It helps downregulate COX-2 and iNOS, involved in producing prostaglandins and nitric oxide.
Modulating the MAPK pathway
The MAPK pathway governs how cells respond to stress and inflammation; astaxanthin helps regulate it, reducing excessive inflammatory signalling.
Proven benefits of Astaxanthin against Inflammation
Clinical studies across different populations have shown astaxanthin’s effects on key markers of inflammation, including CRP, IL-6 and TNF-α, as well as immune response and oxidative stress.
A clinical study from Youssef et al., 2025 found that astaxanthin significantly reduced key inflammatory markers, including IL-6, TNF-α and C-reactive protein (CRP), while improving disease severity scores in patients with pneumonia.
A clinical study from Grigorian et al., 2025 found that astaxanthin supplementation for 8 weeks reduced erythrocyte sedimentation rate (ESR), a clinical marker of inflammation, alongside improvements in clinical outcomes and quality of life in patients with rheumatoid arthritis.
A clinical study by Baralic et al., 2015 found that astaxanthin supplementation for 90 days reduced high-sensitivity CRP and increased salivary IgA in trained soccer players, indicating a reduced systemic inflammatory response and improved redox balance.
A clinical study by Park et al., 2010 found that astaxanthin supplementation for 8 weeks reduced C-reactive protein and 8-OHdG, a marker of oxidative DNA damage, while increasing T- and B-cell proliferation and natural killer cell activity.
Learn about all the anti-inflammatory benefits
Our white paper compiles findings from clinical studies on inflammatory markers, immune response, oxidative stress and systemic inflammation across different populations.
Need a unique formulation for longevity ?
We work with your R&D team to create tailored blends and formula.
Chosen by leading nutraceutical and skincare innovators
Not sure where to start?
Talk to our formulation team & get your free samples in 48 Hours.
Request free samples
Test the quality yourself. We'll ship from Belgium within 48 hours.
Book a consultation
Talk to our experts about formulation, moqs, timelines, and custom solutions.